Efficiency of Spermatogonial Dedifferentiation during Aging
نویسندگان
چکیده
منابع مشابه
Efficiency of Spermatogonial Dedifferentiation during Aging
BACKGROUND Adult stem cells are critical for tissue homeostasis; therefore, the mechanisms utilized to maintain an adequate stem cell pool are important for the survival of an individual. In Drosophila, one mechanism utilized to replace lost germline stem cells (GSCs) is dedifferentiation of early progenitor cells. However, the average number of male GSCs decreases with age, suggesting that ste...
متن کاملExplorer Dopamine and memory dedifferentiation in aging
1 The dedifferentiation theory of aging proposes that a reduction in the specificity of neural 2 representations causes declines in complex cognition as people get older, and may reflect a 3 reduction in dopaminergic signaling. The present pharmacological fMRI study investigated episodic 4 memory-related dedifferentiation in young and older adults, and its relation to dopaminergic 5 function, u...
متن کاملDopamine and memory dedifferentiation in aging
The dedifferentiation theory of aging proposes that a reduction in the specificity of neural representations causes declines in complex cognition as people get older, and may reflect a reduction in dopaminergic signaling. The present pharmacological fMRI study investigated episodic memory-related dedifferentiation in young and older adults, and its relation to dopaminergic function, using a ran...
متن کاملLipid extrusion during dedifferentiation
Clonal cultures of pig-derived mature adipocytes are capable of dedifferentiating and forming proliferative-competent progeny cells in vitro. Initial lipid processing, is different to that observed in cultures of beef-derived adipocytes. Mature pig adipocytes extrude lipid before proliferation, whereas beef-derived adipocytes symmetrically, or asymmetrically, divide without expelling lipid. The...
متن کاملDedifferentiation of emotion regulation strategies in the aging brain.
Different emotion regulation strategies are distinctly represented in the brains of younger adults. Decreasing a reaction to a negative situation by reinterpreting it (reappraisal) relies on cognitive control regions in the prefrontal cortex, while distracting away from a stressor involves more posterior medial structures. In this study, we used Multi-Voxel pattern analyses (MVPA) to examine wh...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: PLoS ONE
سال: 2012
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0033635